When running the remix application, an error occurred: "connect ETIMEDOUT", and the project was terminated

I have encountered a technical problem and I need help.
The command I ran is:shopify app dev --tunnel-url=https://4ee0-222-68-0-86.ngrok-free.app:8080
I use my own tunnel ngrok.
I use proxies to access websites, such as the ClashX application.
I have set the environment variables.
SHOPIFY_HTTPS_PROXY=http://127.0.0.1:7890
SHOPIFY_HTTP_PROXY=http://127.0.0.1:7890
HTTPS_PROXY=http://127.0.0.1:7890
HTTP_PROXY=http://127.0.0.1:7890
The project was functioning properly at the beginning.
The created applications can be displayed in the corresponding developer store’s backend application.
The application was created based on the descriptions in the document, and all the functions are functioning properly.
But less than a minute had passed before…
The terminal displayed an error message and the application was interrupted.
The error message is:

Error: connect ETIMEDOUT 34.111.204.238:443
at TCPConnectWrap.afterConnect [as oncomplete] (node:net:1611:16)
at TCPConnectWrap.callbackTrampoline (node:internal/async_hooks:130:17)

I have tried using proxychains4 to force all Shopify CLI requests to go through a proxy.But it didn’t work.The problem still exists.
I also tried using the default Cloudflare Quick Tunnels.The problem still exists.

Could someone help me solve this problem?

I also encountered the same problem. Have you solved it?